Johann Sebastian Bach’s Goldberg Variations is a contrapuntal tour de force, and one of the pinnacles in the history of the variation genre. Composed ‘to refresh the spirits of music-lovers’, it is a constantly fascinating and deeply enriching evocation of an entire musical universe. This arrangement with two ten-string guitars is a transcription of the original text including later corrections and additional musical indications made by the composer. The additional bass strings of these instruments provide an entire lower octave, giving access to the full range of musical timbres in this eternal masterpiece. Angela Kleger and Dimitar Ivanov founded Duo Synaphé in 2020 to present and record new repertoire for two ten-string guitars. These works were originally written for symphony orchestra, solo piano and other instruments. Having an extra four bass strings, the ten-string guitar offers the striking resonances of an extra octave below the normal guitar. This brings wider flexibility to voicing in arrangements, and retains the extended bass range of piano, harpsichord or other lower range instruments. The nature of these guitars takes classical masterpieces into unknown dimensions of musical expression and sound colors.