As the twenty-first century progresses, the Indo-Pacific theater is experiencing an unprecedented transformation involving economic development, military build-ups, political reforms, social changes, and technological advancements. The region now reflects a multitude of geopolitical challenges, factors, and complicated realities. Although America is still recognized as the most powerful force in the Indo-Pacific region, the challenge to America’s hegemonic role is quite real and unrelenting. The ongoing global financial crisis has left a changed world with unanswered questions in its wake. Is America’s post-WWII dominance of the Indo-Pacific region finally coming to an end? Can the United States and China work together to manage the region’s hegemonic responsibilities? In The Geopolitical Power Shift in the Indo-Pacific Region, Randall Doyle provides analysis and insights on the transformational changes and the epochal history unfolding in this part of the world and America’s increasingly precarious political and economic position.