In the heart of gangland, two novice unlicensed boxing promoters, Turkish (Jason Statham) and Tommy (Stephen Graham) get roped into organising a bare-knuckled fight with local kingpin villain and fellow boxing promoter Brick Top (Alan Ford). But it all goes wrong when Brick Top's fighter, who is rigged to win, is suddenly knocked out by the boys' wildcard Irish gypsy boxer, One Punch Mickey O'Neil (Brad Pitt). Unfortunately things go from bad to worse as Mickey starts playing by his own rules and the duo find they are heading for a whole lot of trouble.